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T. (1996). Busulfan conjugation by glutathione S‐transferases , , and . Drug Metab. Disp. 24, 1015–1019. , and Morel, F. (1998). Genomic organization, 50 ‐flanking region and chromosomal location of the human glutathione transferase A4 gene. Biochem. J. 336, 437–442. , and Guillouzo, A. (2001). Immunohistochemical analysis of glutathione transferase A4 distribution in several human tissues using a specific polyclonal antibody. J. Histochem. Cytochem. 49, 1573–1579. Dirven, H. A. A. , and van Bladeren, P.
Respir. Crit. Care. Med. 166, 457–463. Gilliland, F. , Gauderman, W. , and Dubeau, L. (2002b). Effects of glutathione S‐transferase M1, T1, and P1 on childhood lung function growth. Am. J. Respir. Crit. Care. Med. 166, 710–716. Gilliland, F. , and Diaz‐Sanchez, D. (2004). Effect of glutathione S‐transferase M1 and P1 genotypes on xenobiotic enhancement of allergic responses: Randomized, placebo‐controlled crossover study. Lancet 363, 119–125. , and Guguen‐Guillouzo, C. (2002). Liver protection from apoptosis requires both blockage of initiator caspase activities and inhibition of ASK1/JNK pathway via glutathione S‐transferase regulation.
Pasteur pipets (dropping pipets) $150 mm Â 6 mm id, loosely plugged at tapered end with cotton wool. 2. HPLC equipment (providing at least UV monitor at 214 nm, two solvent gradient system, 1–2 ml injection loop, and integrating capability). 3. com C18, ˚ pore ‘‘Jupiter’’ column; 6‐mm internal diameter, 250‐mm 300A length, 5 M particle size (product number OOG‐4053‐EO). C. GSH‐affinity chromatography (all steps at 4 ) 1. Load GSH agarose suspension into plugged pipet to depth of $13 mm when drained.