Chronic Kidney Diseases - Recent Advances in Clinical and by K. Nitta

By K. Nitta

Continual kidney affliction (CKD) is a growing to be world wide public illness caused by the expanding variety of sufferers with diabetes and high blood pressure, but in addition from the getting older of the inhabitants. because the pathology linked to CKD seems to be to turn into extra advanced with age, it really is necessary to increase the diagnosis of sufferers being affected by CKD by means of constructing potent measures to avoid and keep an eye on issues for the aged. The book handy makes an important contribution to reaching this objective, with well known eastern scientists offering their fresh examine effects. Papers conceal quite a few features of CKD and similar morbidities, starting from dialysis- and access-related concerns to bone problems, tissue engineering, or hyperphosphatemia. as a result of the wide variety of themes provided, this publication may be of curiosity to readers in numerous scientific and learn settings hooked up with the take care of the aged.

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Chronic Kidney Diseases - Recent Advances in Clinical and Basic Research

Continual kidney illness (CKD) is a transforming into around the globe public ailment caused by the expanding variety of sufferers with diabetes and high blood pressure, but in addition from the getting older of the inhabitants. because the pathology linked to CKD appears to be like to turn into extra advanced with age, it really is necessary to enhance the analysis of sufferers struggling with CKD through constructing powerful measures to avoid and keep an eye on issues for the aged.

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Therefore, we focused on iron metabolism and its association with the aforementioned complications in dialysis patients. Despite the importance of the modulation of cellular iron, the mechanisms of iron homeostasis remained one of the least understood areas of iron metabolism until the last decade of the 20th century [4]. Subsequently, several iron transporters involved in its metabolism have been discovered (fig. 1; table 1). Additional important advances in this field were the identification of hepcidin, a serum peptide that is now considered to be the master regulator of iron throughout the body [5], and frataxin, an iron chaperone protein in mitochondria [6].

Jp Hepcidin- and TNF-α-Induced Iron Sequestration Nitta K (ed): Chronic Kidney Diseases – Recent Advances in Clinical and Basic Research. Contrib Nephrol. 1159/000380967) 31 Nitta K (ed): Chronic Kidney Diseases – Recent Advances in Clinical and Basic Research. Contrib Nephrol. 1159/000380968) The Present Status of and Perspectives on Home Hemodialysis Therapy in Japan Ikuto Masakane a, f · Norio Hanafusa b, f · Tomoyuki Kita c, f · Toshio Hasegawa d, f · Kenji Maeda e, f a Yabuki Shima Clinic, Yamagata, b The University of Tokyo Hospital, Department of Hemodialysis and Apheresis, Tokyo, c Sakai Rumi Clinic, Kobe, d Kanagawa Prefectural Shiomidai Hospital, Yokohama, e Daiko Sunadabashi Clinic, Nagoya, f Japanese Society for Home Hemodialysis, Yamagata, Japan Abstract Home hemodialysis (HHD) is one of the best choices for improving the quality of life and survival rate of dialysis patients because it can lead to longer and more frequent dialysis programs to aid in achieving adequate dialysis.

Clin Endocrinol (Oxf) 2008; 69:189–196. 20 Okuno S, Inaba M, Kitatani K, Ishimura E, Yamakawa T, Nishizawa Y: Serum levels of C-terminal telopeptide of type I collagen: a useful new marker of cortical bone loss in hemodialysis patients. Osteoporos Int 2005; 16:501–509. 21 Okuno S, Ishimura E, Kitatani K, Fujino Y, Kohno K, Maeno Y, Maekawa K, Yamakawa T, Imanishi Y, Inaba M, Nishizawa Y: Presence of abdominal aortic calcification is significantly associated with all-cause and cardiovascular mortality in maintenance hemodialysis patients.

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