Chondroitin Sulfate: Structure, Role and Pharmacological by Nicola Volpi

By Nicola Volpi

CS is an unbranched, polydisperse, advanced glycosaminoglycan extracted and purified from quite a few tissues. This polyanion is interacting with either plasma and cells, it can modulate many biochemical and physiologic strategies. as a result presence of sulfate teams in numerous quantities and found in quite a few positions, CS represents a really heterogeneous relatives of polysaccharides. accordingly, the preparative procedure and the analytical suggestions are of paramount value to provide CS with particular constitution and homes and of pharmaceutical grade.

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1999) Polymer Fiber Tetramer Crystal À86 À80 À83 À76 À81 À78 À111 À132 À141 À130 À127 À131 À80 À98 À69 À66 À69 À76 À88 110 66 131 90 94 100 99 À10 80 59 À103 À63 À58 À71 154 À149 À124 46 À85 À124 À149 À10 169 À95 À118 139 À83 À58 À71 108 120 Mixed tetramer Tetramer Molecular dynamics Bayraktar et al. (2004) Bathe et al. 4 linkage)  c  À160 À64 À106 À108 À133 À116 À102 À159 À103 À87 À98 À64 92 97 55 83 À69 À59 À164 À169 À68 À72 162 117 À90 À151 98 À119 À78 À51 À131 51 À91 À126 À103 À121 156 À62 À55 102 c Dermatan sulfate Experimental Mitra et al.

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