Handbook of Pharmaceutical Manufacturing Formulations Volume by Sarfaraz K. Niazi

By Sarfaraz K. Niazi

The 5th quantity within the sequence, this publication covers over the counter items, which come with formulations of goods labeled by way of the U.S. FDA below the OTC class. each one access starts off with a completely proven scaleable production formulation and a precis of producing technique. The ebook presents a close dialogue at the problems encountered in formulating and production OTC items. The part on regulatory and production information offers with the themes of cGMP practices for the OTC drug items, formulations of stable oral dosage varieties, oral suggestions and suspensions, validation of cleansing approach, as well as delivering fast tips about resolving the typical difficulties in formulating OTC medications.

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Turbomachinery: Design and Theory by Martin J.L. Turner

By Martin J.L. Turner

Sincerely offering the idea and layout of turbomachines with step by step approaches and worked-out examples, this reference/text emphasizes basic ideas and development guidance for enclosed rotators, equivalent to pumps and fanatics. includes end-of-chapter challenge and answer units, layout formulations, and equations for transparent knowing of key points in machining functionality, choice, meeting, and building.

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Data Mining in Drug Discovery by Rémy D. Hoffmann, Arnaud Gohier, Pavel Pospisil, Raimund

By Rémy D. Hoffmann, Arnaud Gohier, Pavel Pospisil, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers

Written for drug builders instead of computing device scientists, this monograph adopts a scientific method of mining scientifi c facts resources, protecting all key steps in rational drug discovery, from compound screening to guide compound choice and custom-made medication. truly divided into 4 sections, the 1st half discusses the various info assets to be had, either advertisement and non-commercial, whereas the following part appears on the function and cost of knowledge mining in drug discovery. The 3rd half compares the most typical functions and techniques for polypharmacology, the place information mining can considerably increase the learn attempt. the ultimate portion of the booklet is dedicated to platforms biology methods for compound trying out.
Throughout the ebook, business and educational drug discovery thoughts are addressed, with participants coming from either parts, allowing an educated selection on whilst and which info mining instruments to exploit for one's personal drug discovery project.

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Handbook of Pharmaceutical Manufacturing Formulations Volume by Sarfaraz K. Niazi

By Sarfaraz K. Niazi

The 6th quantity within the six-volume instruction manual of Pharmaceutical production Formulations, this ebook covers the sterile items, which come with formulations of injections, ophthalmic items and different items classified as sterile, from publicly to be had yet extensively dispersed details from FDA New Drug purposes (NDA), patent functions, and different resources of frequent and proprietary formulations. each one access starts off with a completely proven scaleable production formulation and a precis of producing method. The e-book offers a close dialogue at the problems encountered in formulating and production sterile items, the typical components of formula. The part on regulatory and production tips offers with the subjects inspection of sterile items production amenities, new drug program for sterilized items, as well as offering speedy tips about resolving the typical difficulties in formulating sterile items in addition to the scope of info incorporated within the sequence for all dosage varieties.

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Cannabinoids [Handbook of Experimental Pharmacology 168] by Roger G. Pertwee (Ed.), Roger G. Pertwee

By Roger G. Pertwee (Ed.), Roger G. Pertwee

The current booklet is a phenomenal precis of many features of cannabinoid learn. It presents present wisdom in regards to the pharmacology and healing strength of cannabinoids in addition to wisdom in regards to the pharmacology, body structure, and pathology of the endogenous cannabinoid structures. The chapters are written by way of scientists who've made or are nonetheless making significant contributions to the sector. This ebook could support generate novel rules on the right way to procedure the research of emotions.

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Development and Approval of Combination Products: A by Evan B. Siegel

By Evan B. Siegel

A step by step, built-in process for profitable, FDA-approved mixture drug products

utilizing a confirmed built-in method of mixture drug improvement, this e-book publications you step-by-step via all of the preclinical, medical, and production phases. Written from an FDA regulatory point of view, the e-book not just allows you to deliver a profitable mix drug product to marketplace, it additionally units forth the best and powerful route to FDA approval.

The ebook starts off with an introductory bankruptcy proposing definitions and simple regulatory ideas of mixture items. subsequent, it studies production and controls, preclinical checking out versions, pharmacology, medical checking out, regulatory submissions, FDA studies, and approvals. one of the key issues tested are:
* The pharmacology, protection pharmacology, and toxicology aiding human medical trials of mixture products
* methods to medical trial protocol layout and execution
* Chemical, physicochemical, and analytical facets of producing controls and validation that bring about solid elements for blend products
* Key sponsor/FDA conferences and negotiations crucial for approval and commercialization

Case reviews related to such real blend items as Mylotarg, Herceptin, and HercepTest assist you higher know the way to enforce the author's functional instructions. References on the finish of every bankruptcy provide help to locate additional information on any level of the advance, production and approval processes.

This e-book is perfect for researchers, regulators, teachers, undertaking managers, and managers concerned with the advanced means of mixture product improvement. not just does itoffer a complete advisor to the technical facets of the sphere, it additionally integrates all ofthese technical facets right into a unified, powerful method of aid confirm a winning, authorized product.Content:
Chapter 1 evaluation of mixture items improvement and Regulatory evaluate (pages 1–4): Evan B. Siegel
Chapter 2 specific Regulatory techniques to improvement, overview, and Approval (pages 5–75): James Barquest
Chapter three Nonclinical thoughts for profitable Characterization and improvement of mix Drug items (pages 77–111): Duane B. Lakings
Chapter four medical Pharmacology and medical improvement of mixture items (pages 113–170): Chaline Brown
Chapter five Regulatory method concerns for Chemistry, production, and Controls: An built-in procedure (pages 171–200): Patrick L. DeVillier

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How we grieve: relearning the world by Thomas Attig

By Thomas Attig

What can we do while a chum, relative, or family member dies? If we want to comprehend loss event, we needs to study info of survivors' tales. In How We Grieve, Thomas Attig tells real-life stories to demonstrate the poignant disruption of lifestyles and ache that loss includes. He exhibits how via grieving we meet daunting demanding situations, make serious offerings, and reshape our lives. those intimate remedies of coping carry necessary classes that tackle the wishes of grieving humans and those that desire to help and luxury them. The bills advertise realizing of grief itself, motivate admire for individuality and the distinctiveness of loss stories, convey the right way to take care of helplessness within the face of "choiceless" occasions, and gives a lot helpful tips for caregivers. Grieving isn't really a technique of passively dwelling via levels. neither is it a scientific challenge to be solved or controlled by means of others. How We Grieve exhibits that grieving is an lively, coping means of relearning the way to be and act in a global the place loss transforms the cloth of our lives. Loss demanding situations us to relearn issues and areas; relationships with others, together with fellow survivors, the deceased, or even God; and such a lot of all ourselves, together with our everyday life styles and the meanings of our personal lifestyles tales.

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Neumología Clínica by José Luis Álvarez-Sala Walther, Pere Casan Clarà, Felipe

By José Luis Álvarez-Sala Walther, Pere Casan Clarà, Felipe Rodríguez de Castro, Juan Luis Rodríguez Hermosa, Victoria Villena Garrido

  • Nueva edición de una obra que pretende aportar y facilitar información rigurosa y equilibrada sobre todos los problemas respiratorios que puedan plantearse ante un médico asistencial.
  • Los autores actualizan todos los contenidos, manteniendo los 100 capítulos de l. a. anterior edición, agrupados en sixteen secciones, y prestando especial atención a aquellas áreas en las que se han producido más novedades terapéuticas y diagnósticas a lo largo de los últimos años.
  • Los avances en enfermedad pulmonar obstructiva crónica (EPOC), cáncer de pulmón, asma o apnea del sueño son algunas de las áreas en las que se han producido más novedades y cuyos avances se recogen en esta nueva edición.
  • Participan en l. a. obra más de one hundred seventy autores, todos ellos destacados expertos en el área de los angeles neumología.

Segunda edición que continúa con los angeles exertions de ofrecer una formación completa, rigurosa y accesible sobre los problemas respiratorios a los que se enfrentan los neumólogos en su práctica clínica.

Recoge, en esta nueva edición, tanto los más novedosos conocimientos patogénicos y fisiopatológicos relevantes para esta especialidad como los últimos avances diagnósticos y terapéuticos en neumología.

Siguiendo este objetivo de renovación, las referencias bibliográficas han sido completamente actualizadas y se han incorporado numerosas figuras, tablas y cuadros nuevos.

No solo los especialistas en neumología, sino también los internistas y los médicos de atención primaria, se beneficiarán de los conocimientos y l. a. experiencia de los más de one hundred seventy expertos que firman los a hundred capítulos que constituyen los angeles obra.

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LANGE Instant Access Acid-Base, Fluids, and Electrolytes by Robert F. Reilly, Mark Perazella

By Robert F. Reilly, Mark Perazella

Essential Evidence-Based facts for universal scientific Encounters

"This is particularly valuable for services who need a speedy evaluation of fluid, electrolyte, and acid-base problems with out soliciting for in-depth info. history information regarding pathophysiology and references should not incorporated, yet are usually not wanted. This makes the ebook designated and relatively diverse from different on hand assets at the subject. three Stars."--Doody's overview Service

Make experience of acid-base and electrolytes with this compact, on-the-go guide--filled with medical evidence, figures, and data.

In this ultra-convenient source, the authors have distilled down the main appropriate insights from their acclaimed textual content Nephrology in 30 Days, providing you with an entire, but concise assessment of acid-based and electrolytes--supported by way of evidence-based findings.

You'll locate at-a-glance tables and a bulleted layout that places key diagnostic and medical details correct at your fingertips. This one-stop consultant will get you up to the mark at the significant matters in acid-base and electrolyte disturbances, from metabolic acidosis to serum calcium issues. it is the ideal medical significant other to extra in-depth acid-base texts--one that is going past academic rules to target the true global of medical drugs and sufferer management.

  • The excellent transportable mind for the wards
  • Vital evidence and figures every person forgets to recollect
  • Presented in easy-access tables

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