Assembly Instructions for Polypeptide Models. Academic by Edward J. Barrett

By Edward J. Barrett

Meeting directions for Polypeptide types presents meeting techniques for? polypeptide chains and for modeling the ?-helix and the parallel and antiparallel ?-pleated sheets.

This textual content is split into 9 chapters and begins with a short advent to the fundamental unit of polypeptide or protein constitution, that's the amino acid. the next chapters care for the elements of the version approach, together with the torsion angles and the uneven ?-carbon atom. the rest chapters current particular directions for the development of unfastened amino acids, polypeptide finish teams, aspect chain teams, secondary constructions, and facet chain torsion angles.

This ebook will end up worthwhile to protein and peptide scientists, natural chemists, and biochemists.

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Additional info for Assembly Instructions for Polypeptide Models. Academic Press/Molecular Design Inc. Precision Molecular Models

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8cm) long to form the hydrogen bonds connecting the two strands. Remember to align the strands in different directions, as shown schematically below. Figure 14 shows a model of this structure with space-filling hydrogen atoms at each a -carbon, making polyglycine strands. o H3N~ C II /C, a /~ H 0 H J II J /N, N C • • • • • • 'II H 0 /c, /~ Co N /N, /COO- I C II • • • • • • H C-terminus Co 0 N-terminus THE PARALLEL P -PLEATED SHEET To construct a model of the P -parallel pleated sheet, at least two strands must be constructed.

Remember to align the strands in different directions, as shown schematically below. Figure 14 shows a model of this structure with space-filling hydrogen atoms at each a -carbon, making polyglycine strands. o H3N~ C II /C, a /~ H 0 H J II J /N, N C • • • • • • 'II H 0 /c, /~ Co N /N, /COO- I C II • • • • • • H C-terminus Co 0 N-terminus THE PARALLEL P -PLEATED SHEET To construct a model of the P -parallel pleated sheet, at least two strands must be constructed. In these polypeptides the 0 angles are -119° ( ~O fastener) and the'" angles, +113° ( / 5) • Again, use silicone tubing for the hydrogen bonds connecting the strands 0 In this case the two connected strands run in the same direction.

8cm) long to form the hydrogen bonds connecting the two strands. Remember to align the strands in different directions, as shown schematically below. Figure 14 shows a model of this structure with space-filling hydrogen atoms at each a -carbon, making polyglycine strands. o H3N~ C II /C, a /~ H 0 H J II J /N, N C • • • • • • 'II H 0 /c, /~ Co N /N, /COO- I C II • • • • • • H C-terminus Co 0 N-terminus THE PARALLEL P -PLEATED SHEET To construct a model of the P -parallel pleated sheet, at least two strands must be constructed.

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